Ghrelin, Appetite Regulation, and Food Reward: Interaction with Chronic Stress
2011

Ghrelin, Appetite Regulation, and Food Reward: Interaction with Chronic Stress

publication Evidence: moderate

Author Information

Author(s): Yolanda Diz-Chaves

Primary Institution: Instituto Cajal, CSIC, Madrid, Spain

Hypothesis

Does ghrelin play a role in the pathophysiology of obesity and eating disorders through its interaction with the corticotropin-releasing-factor system and chronic stress?

Conclusion

Ghrelin is a significant regulator of appetite and food reward, particularly in the context of chronic stress.

Supporting Evidence

  • Ghrelin is implicated in food reward and can override feelings of fullness.
  • Chronic stress can increase ghrelin levels, influencing eating behavior.
  • Ghrelin interacts with the corticotropin-releasing-factor system, affecting energy balance.

Takeaway

Ghrelin is a hormone that makes you feel hungry and can make you want to eat even when you're not hungry, especially when you're stressed.

Digital Object Identifier (DOI)

10.1155/2011/898450

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