Enhanced tuberculosis case detection among substitution treatment patients: a randomized controlled trial
2011

Improving TB Screening for Drug Users

Sample size: 112 publication 10 minutes Evidence: moderate

Author Information

Author(s): Rüütel Kristi, Loit Helle-Mai, Sepp Tiiu, Kliiman Kai, McNutt Louise-Anne, Uusküla Anneli

Primary Institution: National Institute for Health Development, Estonia

Hypothesis

Can a case management intervention increase tuberculosis screening and treatment entry among injecting drug users referred from a methadone treatment program?

Conclusion

The study shows that a more active referral approach significantly increases attendance to TB screening services among injecting drug users.

Supporting Evidence

  • 59% of invited participants took part in the study.
  • 30% of the control group attended TB services compared to 57% in the case management group.
  • None of the participants were diagnosed with TB.

Takeaway

This study found that helping drug users get to TB clinics can make them more likely to get tested for tuberculosis.

Methodology

A randomized controlled trial was conducted to evaluate a case management intervention for increasing TB screening among injecting drug users.

Potential Biases

High HIV prevalence among participants may not represent the broader injecting drug user population.

Limitations

The small sample size and recruitment from only one center limit the generalizability of the findings.

Participant Demographics

Participants were primarily injecting drug users, with 86% HIV-positive and a mean age of 26.2 years.

Statistical Information

P-Value

0.004

Confidence Interval

95% CI 1.4-10.4

Statistical Significance

p = 0.004

Digital Object Identifier (DOI)

10.1186/1756-0500-4-192

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