Enteropathogenic E. coli, Salmonella, and Shigella: Masters of Host Cell Cytoskeletal Exploitation
1999
How Bacteria Exploit Host Cell Structures
publication
Author Information
Author(s): Danika L. Goosney, Derek G. Knoechel, B. Brett Finlay
Primary Institution: University of British Columbia
Hypothesis
Bacterial pathogens have evolved strategies to exploit host cellular processes for survival.
Conclusion
Bacterial pathogens like E. coli, Salmonella, and Shigella have developed mechanisms to hijack host cell cytoskeletons, leading to significant disease.
Supporting Evidence
- Bacterial pathogens can adhere tightly to host cells or invade them to survive.
- E. coli causes severe diarrhea by forming lesions on intestinal cells.
- Salmonella invades intestinal cells and induces membrane ruffling.
- Shigella moves from cell to cell by using actin tails.
Takeaway
Some bacteria can trick our body's cells to help them survive and move around inside us, which can make us sick.
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