HPV Infections in Jamaican Women
Author Information
Author(s): Watt Angela, Garwood David, Jackson Maria, Younger Novie, Ragin Camille, Smikle Monica, Fletcher Horace, McFarlane-Anderson Norma
Primary Institution: University of the West Indies, Kingston, Jamaica
Hypothesis
This study aims to determine the genotypes commonly found in high-risk and multiple HPV infections in cancer-free Jamaican women.
Conclusion
The HPV genotype distribution in Jamaican women differs from that found in Europe, North America, and some parts of Asia, suggesting the need for vaccines targeting local genotypes.
Supporting Evidence
- HPV DNA was detected in 87.7% of the sample.
- 80.2% of HPV-positive women had high-risk infections.
- HPV types 45 and 58 were the most common high-risk types found.
- 93.6% of women with high-risk infections had normal cytology.
- Bacterial vaginosis was associated with multiple infections.
Takeaway
The study found that many Jamaican women have high-risk HPV infections, which are different from those seen in other countries, meaning local vaccines might be needed.
Methodology
Cervical cell samples were collected and HPV DNA was detected using Polymerase Chain Reaction and Reverse Line Hybridization.
Potential Biases
Potential selection bias due to the recruitment of women from specific clinics.
Limitations
The study may not represent all Jamaican women as it focused on specific clinics and demographics.
Participant Demographics
The study included 120 pregnant women aged 15–44 and 116 non-pregnant women aged 19–83.
Statistical Information
Confidence Interval
1.26–9.82
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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