frmaTools: A New R Package for Microarray Data Analysis
Author Information
Author(s): Matthew N McCall, Rafael A Irizarry
Primary Institution: University of Rochester Medical Center
Hypothesis
Can a new R package improve the usability of the fRMA algorithm for microarray data analysis?
Conclusion
The frmaTools package allows users to easily create their own fRMA implementations, enhancing the applicability of the fRMA algorithm.
Supporting Evidence
- The frmaTools package is freely available as part of the Bioconductor project.
- fRMA allows for individual array preprocessing while retaining multi-array advantages.
- The study demonstrates that fRMA performs well even with limited data.
Takeaway
This study introduces a new tool that helps scientists analyze microarray data more easily by allowing them to create their own data processing methods.
Methodology
The study describes the development of the frmaTools R package, which facilitates the creation of frozen parameter vectors for the fRMA algorithm.
Limitations
The fRMA algorithm requires a curated database of microarrays, limiting its implementation to certain platforms.
Digital Object Identifier (DOI)
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