Harlequin Syndrome in a Case of Toxic Goitre: A Rare Association
2011

Harlequin Syndrome Linked to Toxic Goitre

Sample size: 1 publication Evidence: low

Author Information

Author(s): Pradeep P. V., Benede Ajith K., Harshita Skandha S., Jayashree B.

Primary Institution: Narayana Medical College & Superspeciality Hospital

Hypothesis

Can Harlequin syndrome occur in patients with autoimmune hyperthyroidism?

Conclusion

Harlequin syndrome persisted in a patient after total thyroidectomy for toxic goitre, suggesting a possible autoimmune origin.

Supporting Evidence

  • Harlequin syndrome is usually benign but can indicate serious underlying conditions.
  • Increased sweating is common in hyperthyroid patients and usually resolves after treatment.
  • The patient experienced unilateral sweating that persisted after surgery.

Takeaway

A woman with a thyroid problem had a rare condition called Harlequin syndrome, which made one side of her face sweat more than the other, and it didn't go away even after surgery.

Methodology

Case report detailing the patient's symptoms, diagnosis, treatment, and follow-up.

Limitations

The autoimmune theory is limited by the fact that the right side sympathetic chain was spared.

Participant Demographics

A 36-year-old female patient.

Digital Object Identifier (DOI)

10.1155/2011/293076

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