Innate Antiviral Response: Role in HIV-1 Infection
2011
Innate Antiviral Response: Role in HIV-1 Infection
publication
10 minutes
Evidence: moderate
Author Information
Author(s): Pitha Paula M.
Primary Institution: Johns Hopkins University
Hypothesis
What is the role of the innate antiviral response in regulating HIV-1 infection?
Conclusion
The innate antiviral response plays a critical role in the regulation of HIV-1 infection and pathogenicity.
Supporting Evidence
- The innate immune response is essential for survival against invading pathogens.
- Type I interferons are critical components of the innate antiviral response.
- IRF family transcription factors play a major role in the induction of antiviral responses.
Takeaway
When viruses like HIV-1 invade the body, our immune system quickly responds to fight them off. This response is really important for keeping us healthy.
Methodology
This review summarizes current knowledge on the mechanisms of the innate antiviral response, focusing on its role in HIV-1 infection.
Limitations
The review does not provide new experimental data but summarizes existing literature.
Digital Object Identifier (DOI)
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