FANS: A Tool for Analyzing Genetic Variations
Author Information
Author(s): Liu Chuan-Kun, Chen Yan-Hau, Tang Cheng-Yang, Chang Shu-Chuan, Lin Yi-Jung, Tsai Ming-Fang, Chen Yuan-Tsong, Yao Adam
Primary Institution: National Genotyping Center (NGC), Academia Sinica, Taipei, Taiwan
Hypothesis
Can FANS streamline the functional analysis of novel SNPs and mutations in human and mouse genomes?
Conclusion
FANS significantly simplifies the analysis operations to a four-step procedure while still covering all major areas of interest to researchers.
Supporting Evidence
- FANS can process any point change in coding regions or splice sites to assess disease risk.
- The program categorizes variations into risk types and levels for prioritization.
- FANS reduces the time for analysis from over an hour to less than two minutes.
Takeaway
FANS is a tool that helps scientists quickly analyze genetic changes by making the process easier and faster, so they can focus on their research.
Methodology
FANS automates the analysis flow and simplifies operations for genetic variation analysis.
Limitations
The tool currently processes a maximum of 100 variations per batch query to avoid overloading source websites.
Digital Object Identifier (DOI)
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