Detection of a Cis eQTL Controlling BMCO1 Gene Expression Leads to the Identification of a QTG for Chicken Breast Meat Color
2011

Identifying the Gene for Chicken Breast Meat Color

Sample size: 373 publication 10 minutes Evidence: high

Author Information

Author(s): Le Bihan-Duval Elisabeth, Nadaf Javad, Berri Cécile, Pitel Frédérique, Graulet Benoît, Godet Estelle, Leroux Sophie Y., Demeure Olivier, Lagarrigue Sandrine, Duby Cécile, Cogburn Larry A., Beaumont Catherine M., Duclos Michel J.

Primary Institution: INRA, UR83, Recherches Avicoles, Nouzilly, France

Hypothesis

Can we identify the gene controlling the color of chicken breast meat?

Conclusion

The study identified the BCMO1 gene as the key regulator of chicken breast meat color through a specific genetic mutation.

Supporting Evidence

  • BCMO1 mRNA levels were higher in high-growth chickens compared to low-growth chickens.
  • A significant negative correlation was found between BCMO1 mRNA levels and breast meat yellowness.
  • Two SNPs in the BCMO1 promoter were linked to variations in meat color.
  • The identified haplotypes showed significant differences in BCMO1 expression and meat color.
  • Carotenoid content in breast muscle was higher in chickens with the GN57G haplotype.

Takeaway

Scientists found a gene that affects the color of chicken meat, which can help farmers produce better quality chicken.

Methodology

The study combined quantitative trait loci (QTL) analysis and gene expression analysis to identify the BCMO1 gene's role in meat color.

Limitations

The study focused on specific chicken lines and may not be generalizable to all breeds.

Participant Demographics

The study involved F2 chickens from high-growth and low-growth lines.

Statistical Information

P-Value

p<0.0001

Confidence Interval

14.4–18.4 Mb

Statistical Significance

p<0.0001

Digital Object Identifier (DOI)

10.1371/journal.pone.0014825

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