Comparison of Devices Used for Stent-Assisted Coiling of Intracranial Aneurysms Neuroform vs. Enterprise Stent
2011

Comparison of Devices Used for Stent-Assisted Coiling of Intracranial Aneurysms: Neuroform vs. Enterprise Stent

Sample size: 356 publication Evidence: moderate

Author Information

Author(s): Izar Benjamin, Rai Ansaar, Raghuram Karthikram, Rotruck Jill, Carpenter Jeffrey

Primary Institution: Massachusetts General Hospital, Boston, Massachusetts, United States of America

Hypothesis

Is there a difference in the effectiveness and safety of the Neuroform and Enterprise stents for stent-assisted coiling of intracranial aneurysms?

Conclusion

The Enterprise stent has a higher procedural success rate than the Neuroform stent, but both stents show similar characteristics in terms of complications and outcomes.

Supporting Evidence

  • The Enterprise stent had a higher stenting success rate compared to the Neuroform stent.
  • Both stents showed similar rates of peri-procedural complications.
  • 36.1% of followed aneurysms in the stent-assisted coiling group showed progressive occlusion.

Takeaway

Doctors compared two types of stents used to treat brain aneurysms and found that one worked better for getting into place, but both were safe and effective.

Methodology

A retrospective analysis of 356 patients with 385 aneurysms treated with either Neuroform or Enterprise stents, comparing procedural success, complications, and outcomes.

Potential Biases

Potential bias due to the retrospective nature of the study and the single-center design.

Limitations

The study is retrospective and conducted at a single center, which may limit the generalizability of the findings.

Participant Demographics

356 patients with 385 aneurysms, including 86 patients treated with stent-assisted coiling.

Statistical Information

P-Value

p=0.0329

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1371/journal.pone.0024875

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