Assessing Agreement in Embryo Evaluation During IVF
Author Information
Author(s): Paternot Goedele, Wetsels Alex M, Thonon Fabienne, Vansteenbrugge Anne, Willemen Dorien, Devroe Johanna, Debrock Sophie, D'Hooghe Thomas M, Spiessens Carl
Primary Institution: Leuven University Fertility Centre, UZ Gasthuisberg, Leuven, Belgium
Hypothesis
Can multilevel images improve intra- and inter-observer agreement in embryo evaluation?
Conclusion
A simple website can facilitate quality control in embryo scoring, showing good to excellent agreement for certain characteristics.
Supporting Evidence
- Good to excellent intra-observer agreement was found for the position of the pronuclei on day 1.
- The number of blastomeres on day 2 and day 3 showed good to excellent agreement.
- Clinical decision making had high agreement among embryologists.
- Moderate to very poor agreement was observed for other embryo characteristics.
Takeaway
This study looked at how well different doctors agree when checking embryos for IVF. They found that using special images helps them agree more.
Methodology
Five embryologists evaluated multilevel images of embryos at different stages to assess agreement in embryo morphology.
Potential Biases
Potential bias due to the subjective nature of embryo evaluation.
Limitations
The study may not fully represent routine embryo populations as it focused on specific characteristics.
Participant Demographics
Five embryologists from four different IVF centers participated.
Digital Object Identifier (DOI)
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