Risk of Dengue Hemorrhagic Fever from Dengue-3 in Mexico
Author Information
Author(s): Baltasar Briseno-Garcia, Hector Gomez-Dantes, Enid Argott-Ramirez, Raul Montesano, Ana-Laura Vazquez-Martinez, Sergio Ibanez-Bernal, Guillermina Madrigal-Ayala, Cuauhtemoc Ruiz-Matus, Ana Flisser, Roberto Tapia-Conyer
Primary Institution: Instituto Nacional de Diagnostico y Referencia Epidemiologicos, Secretaria de Salud, Mexico D.F., Mexico
Hypothesis
The emergence of dengue serotype DEN-3 in Mexico increases the risk of dengue hemorrhagic fever (DHF).
Conclusion
The identification of DEN-3 in Mexico poses a potential risk for future DHF outbreaks due to the population's susceptibility.
Supporting Evidence
- Dengue hemorrhagic fever cases in Mexico increased significantly in 1995.
- DEN-3 was identified in 19 patients with classic dengue fever in 1995.
- Surveillance for dengue cases began in 1982, identifying 681 dengue virus isolates by 1995.
- The prevalence of dengue serotypes changed significantly in 1995 compared to previous years.
- Population movements may facilitate the spread of DEN-3 to susceptible areas.
Takeaway
Dengue-3, a type of dengue virus, has been found in Mexico, which could make people very sick if they get infected.
Methodology
Surveillance and identification of dengue virus serotypes through serologic evidence and epidemiological data.
Potential Biases
Potential underestimation of dengue cases due to misdiagnosis and lack of medical care demand.
Limitations
The study does not fully determine the cost of DHF cases or the effectiveness of current health resources.
Participant Demographics
Population in Mexico, particularly in tropical and subtropical areas.
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