GeNESiS: gene network evolution simulation software
2008

GeNESiS: Gene Network Evolution Simulation Software

publication Evidence: moderate

Author Information

Author(s): Anton Kratz, Masaru Tomita, Arun Krishnan

Primary Institution: Institute for Advanced Biosciences, Keio University

Hypothesis

The software provides a way for researchers to understand the evolutionary behavior of populations of gene regulatory networks (GRNs).

Conclusion

GeNESiS will serve as a useful tool for scientists interested in understanding the evolution of gene regulatory networks under various conditions.

Supporting Evidence

  • The software models gene regulation using finite-state and stochastic models.
  • GeNESiS allows users to simulate evolution under different selective pressures.
  • The software is designed to help understand the evolutionary mechanisms of GRNs.

Takeaway

GeNESiS is a computer program that helps scientists see how gene networks change and grow over time, like how plants grow in different weather.

Methodology

The software uses a genetic algorithm to simulate the evolution of gene regulatory networks based on varying selective pressures and starting conditions.

Digital Object Identifier (DOI)

10.1186/1471-2105-9-541

Want to read the original?

Access the complete publication on the publisher's website

View Original Publication