H5N1 Virus Evolution in Europe
Author Information
Author(s): Cattoli Giovanni, Fusaro Alice, Monne Isabella, Capua Ilaria
Primary Institution: Istituto Zooprofilattico Sperimentale delle Venezie
Hypothesis
What is the evolution and molecular epidemiology of HPAI A/H5N1 in Europe?
Conclusion
The study provides a comprehensive overview of the evolution and spread of HPAI A/H5N1 in Europe, highlighting the dominance of clade 2.2.
Supporting Evidence
- HPAI A/H5N1 has caused outbreaks in poultry and wild birds in 62 countries, including 24 in Europe.
- Clade 2.2 was the dominant strain spreading from Asia to Europe.
- Genetic diversity of HPAI A/H5N1 viruses has been documented in multiple European countries.
- Phylogenetic analysis indicates widespread gene flow of H5N1 viruses throughout Europe.
Takeaway
This study looks at how a bird flu virus called H5N1 has changed and spread in Europe over the years, showing that one type of the virus has been the most common.
Methodology
The study involved phylogenetic and gene migrational analysis of HPAI A/H5N1 sequences from Europe.
Limitations
The study is not complete due to the unavailability of virus sequences from some infected countries.
Digital Object Identifier (DOI)
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