Isotretinoin and Central Retinal Vein Occlusion in a Teenager
Author Information
Author(s): Labiris Georgios, Katsanos Andreas, Karapetsa Maria, Mpanaka Ioanna, Chatzoulis Dimitrios
Primary Institution: University Hospital of Larissa
Hypothesis
Isotretinoin use may increase the risk of central retinal vein occlusion even in patients with minimal predisposition for thrombotic incidents.
Conclusion
Isotretinoin use may be associated with serious thrombotic effects in young patients with minimal risk factors.
Supporting Evidence
- The patient had a heterozygous mutation associated with a minor risk for thrombosis.
- Isotretinoin was discontinued after the diagnosis of central retinal vein occlusion.
- Previous reports have indicated an association between isotretinoin and thrombotic events.
Takeaway
A 17-year-old boy developed a serious eye problem after taking a medication for acne, even though he didn't have many risk factors for blood clots.
Methodology
Case report detailing the clinical presentation, investigations, and treatment of a patient with central retinal vein occlusion.
Limitations
The study is based on a single case report, limiting generalizability.
Participant Demographics
17-year-old white male.
Digital Object Identifier (DOI)
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