ASSOCIATION OF DIABETES WITH OLFACTION IN OLDER ADULTS: THE ATHEROSCLEROSIS RISK IN COMMUNITIES (ARIC) STUDY
2024

Diabetes and Smell in Older Adults

Sample size: 6122 publication Evidence: moderate

Author Information

Author(s): Pleasants Hanna, Chen Honglei, Mosley Tom, Chamberlin Keran, Yuan Yaqun, Shrestha Srishti, Pinto Jayant, Kucharska-Newton Anna

Primary Institution: University of North Carolina, Chapel Hill

Hypothesis

Is there a long-term association between diabetes and olfactory impairment in older adults?

Conclusion

The study found that diabetes in midlife is associated with poorer olfactory function in older age.

Supporting Evidence

  • Diabetes prevalence at midlife was associated with poor olfaction in older adulthood.
  • Greater HbA1c in midlife was linked to lower olfaction scores in older adulthood.
  • Associations were weaker when diabetes and HbA1c were measured in older adulthood.

Takeaway

If you have diabetes when you're younger, it might make it harder to smell things when you're older.

Methodology

The study used binary logistic regression and linear regression to analyze the association between diabetes and olfaction.

Participant Demographics

58.6% female, 22.7% Black race, mean age 55.0 at midlife and 75.8 at older adulthood.

Statistical Information

Confidence Interval

1.02, 1.53

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1093/geroni/igae098.2398

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