Rapid Increase of Resistance to Erythromycin and Clindamycin in Streptococcus pyogenes in Italy, 1993-1995
1996

Increase of Antibiotic Resistance in Streptococcus pyogenes in Italy

Sample size: 1253 publication Evidence: moderate

Author Information

Author(s): Giuseppe Cornaglia, Marco Ligozzi, Annarita Mazzariol, Myriam Valentini, Graziella Orefici, Roberta Fontana

Primary Institution: Institute of Microbiology, University of Verona, Italy

Hypothesis

Is there a rising trend in antibiotic resistance among Streptococcus pyogenes in Italy?

Conclusion

The study found a significant increase in erythromycin resistance among Streptococcus pyogenes strains in Italy from 1993 to 1995.

Supporting Evidence

  • In 1993, the average incidence of erythromycin-resistant strains was 5.1%.
  • By 1995, the incidence increased to a mean value of 26.8%.
  • Resistance to clindamycin was also noted, but data was limited.

Takeaway

Doctors need to be careful because more and more germs that cause throat infections are not getting better with common antibiotics like erythromycin.

Methodology

Data was collected from 15 laboratories over three years, testing throat swabs from symptomatic patients for antibiotic resistance.

Limitations

The study only included data from specific geographic areas and may not represent the entire country.

Participant Demographics

Mostly school-age outpatients from various geographic areas in Italy.

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