HEARING AND OLFACTORY LOSS ASSOCIATED WITH ALTERED BRAIN STRUCTURE AND CONNECTIVITY IN DEMENTIA RISK
2024

Sensory Loss and Dementia Risk

Sample size: 597 publication

Author Information

Author(s): Phillips Natalie, Best Tristin, Grant Nicole, Kabir Ameera, Pichora-Fuller M Kathleen, Campos Jennifer, Mick Paul, Wittich Walter

Primary Institution: Concordia University

Hypothesis

Are sensory factors associated with alterations in brain function and structure in older adults with or at risk for dementia?

Conclusion

Sensory loss is common in older adults and is linked to changes in brain function and structure, particularly in those at risk for dementia.

Supporting Evidence

  • Sensory loss in hearing, vision, and olfaction is prevalent in older adults.
  • Normal sensory performance was observed in a minority of participants.
  • Deficits in multiple sensory domains were highly prevalent among participants with Alzheimer's disease.

Takeaway

As people get older, losing the ability to hear, see, or smell can happen a lot, and it might mean they could get dementia.

Methodology

Participants were assessed for sensory loss using pure-tone screening for hearing, contrast sensitivity for vision, and the Brief Smell Identification Test for olfaction.

Participant Demographics

Participants included 128 with normal cognition, 135 with subjective cognitive decline, 241 with mild cognitive impairment, and 93 with Alzheimer's disease.

Digital Object Identifier (DOI)

10.1093/geroni/igae098.1996

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