Neuromuscular electrical stimulation and biofeedback therapy may improve endometrial growth for patients with thin endometrium during frozen-thawed embryo transfer: A preliminary report
2011

Improving Endometrial Growth with Neuromuscular Electrical Stimulation

Sample size: 41 publication Evidence: moderate

Author Information

Author(s): Bodombossou-Djobo Madafeiton, Zheng Chengyu, Chen Shaoqing, Yang Dongzi

Primary Institution: Memorial Hospital of Sun Yat-Sen University

Hypothesis

Can pelvic floor neuromuscular electrical stimulation therapy improve endometrial thickness in women with thin endometrium during frozen-thawed embryo transfer?

Conclusion

Neuromuscular electrical stimulation therapy may be effective for patients with a thin endometrium.

Supporting Evidence

  • 60% of patients in the NMES group achieved endometrial thickness of 8 mm or more after treatment.
  • The mean endometrial thickness increased significantly from 5.60 mm to 7.93 mm in the NMES group.
  • The pregnancy rate in the NMES group was 42%, compared to 35% in the control group.

Takeaway

This study tested a special therapy to help women with thin uterine linings get thicker linings, which might help them get pregnant.

Methodology

41 patients with thin endometrium were treated with pelvic floor neuromuscular electrical stimulation therapy and their endometrial thickness was measured before and after treatment.

Limitations

The study had a small sample size and further studies are needed to confirm the findings.

Participant Demographics

Women aged 20 to 39 with a history of infertility and thin endometrium.

Statistical Information

P-Value

0.002

Statistical Significance

p=0.002

Digital Object Identifier (DOI)

10.1186/1477-7827-9-122

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