Finding Bidirectional Promoters in Arabidopsis thaliana
Author Information
Author(s): Wang Quan, Wan Lin, Li Dayong, Zhu Lihuang, Qian Minping, Deng Minghua
Primary Institution: Peking University
Hypothesis
No genome-wide analysis of bidirectional genes for plants has been done.
Conclusion
Bidirectional gene pairs are prevalent in the plant genome, and analyzing their intergenic regions could provide new insights into gene regulation.
Supporting Evidence
- 2471 bidirectional gene pairs were identified in the Arabidopsis thaliana genome.
- Bidirectional genes tend to be coexpressed and involved in similar biological functions.
- Functionally associated bidirectional genes have higher expression correlation.
Takeaway
Scientists looked at a plant's genes and found many pairs that work together, which might help us understand how genes are controlled.
Methodology
A genome-wide survey was conducted to identify bidirectional gene pairs and analyze their intergenic regions for regulatory elements.
Limitations
The study focused only on Arabidopsis thaliana and did not include chloroplast or mitochondrial genomes.
Statistical Information
P-Value
1.33 × 10-3
Statistical Significance
p < 2.2 × 10-16
Digital Object Identifier (DOI)
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