A Star in the Brainstem Reveals the First Step of Cortical Magnification
2011

A Star in the Brainstem Reveals the First Step of Cortical Magnification

Sample size: 9 publication Evidence: moderate

Author Information

Author(s): Catania Kenneth C., Leitch Duncan B., Gauthier Danielle

Primary Institution: Department of Biological Sciences, Vanderbilt University, Nashville, Tennessee, United States of America

Hypothesis

Where does the preferential allocation of neural tissue to important afferents first occur in the somatosensory system?

Conclusion

The study found that the principal trigeminal nucleus (PrV) in star-nosed moles provides the first step in magnifying central nervous system representations of important sensory afferents.

Supporting Evidence

  • PrV in star-nosed moles is greatly expanded compared to other species.
  • The largest representation in PrV corresponds to the tactile fovea, ray 11.
  • Ray volumes in PrV correlate closely with the number of afferents from each ray.
  • Ray 11 receives 11% of the afferent fibers but takes up 25% of the cortical representation.

Takeaway

Scientists studied the brains of star-nosed moles to see how their important sensory areas are represented, finding that the brainstem helps make these areas bigger.

Methodology

Electrophysiological recordings and brainstem sections were used to analyze the representation of nasal rays in the principal trigeminal nucleus.

Potential Biases

Potential bias in the selection of moles and the methods used for measuring brain structures.

Limitations

The study was limited to a small sample size of star-nosed moles and one hairy-tailed mole.

Participant Demographics

8 star-nosed moles and 1 hairy-tailed mole collected in Northern Pennsylvania.

Statistical Information

P-Value

0.001

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1371/journal.pone.0022406

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