Psychiatric Disorders in Early-Onset vs. Late-Onset Dementia
Author Information
Author(s): Qi Xiang, Vranceanu Ana-Maria, Wu Bei
Primary Institution: New York University
Hypothesis
This study investigates the relationship between early-onset dementia and psychiatric disorders compared to late-onset dementia and individuals without dementia.
Conclusion
Individuals with early-onset dementia are at a higher risk for various psychiatric disorders compared to those with late-onset dementia and those without dementia.
Supporting Evidence
- Early-onset dementia affects approximately 200,000 Americans.
- Individuals with early-onset dementia showed increased risks of depression, anxiety, bipolar disorder, schizophrenia, and substance use.
- The differences in psychiatric risks were more pronounced when comparing early-onset dementia to individuals without dementia.
Takeaway
People diagnosed with dementia before age 65 are more likely to have mental health issues than those diagnosed later or those without dementia.
Methodology
Retrospective cohort study using electronic health records.
Participant Demographics
The cohort included 59.7% women with a mean age of 52.3.
Statistical Information
Confidence Interval
95% CI 1.23-1.76 for depression, 95% CI 1.23-1.75 for anxiety, etc.
Digital Object Identifier (DOI)
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