Viruses, Autophagy Genes, and Crohn’s Disease
2011

Viruses, Autophagy Genes, and Crohn’s Disease

publication Evidence: moderate

Author Information

Author(s): Vanessa M. Hubbard, Ken Cadwell

Primary Institution: Skirball Institute of Biomolecular Medicine, Department of Microbiology, New York University School of Medicine

Hypothesis

The study examines the relationship between viruses, autophagy genes, and Crohn’s disease.

Conclusion

The interaction between specific viruses and genetic susceptibility can influence the development of Crohn’s disease.

Supporting Evidence

  • Crohn's disease is linked to genetic factors and environmental agents.
  • Viruses may play a role in the disease, but more research is needed.
  • Certain bacteria can exacerbate Crohn's disease in genetically susceptible individuals.

Takeaway

Some germs and genes can work together to make people sick with Crohn's disease, which affects the tummy.

Methodology

The review analyzes existing epidemiological, genetic, and experimental evidence regarding the role of viruses and autophagy in Crohn's disease.

Limitations

The review does not provide new experimental data and relies on existing literature.

Digital Object Identifier (DOI)

10.3390/v3071281

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