Muscle specific differences in the regulation of myogenic differentiation in chickens genetically selected for divergent growth rates
2011

Muscle Differences in Chickens Selected for Growth Rates

Sample size: 112 publication 10 minutes Evidence: moderate

Author Information

Author(s): Al-Musawi Sara L., Lock Francesca, Simbi Biggy H., Bayol Stéphanie A.M., Stickland Neil C.

Primary Institution: Royal Veterinary College

Hypothesis

Broilers will exhibit increased embryonic activity related to differing expression levels of myogenic regulatory factors and IGFs.

Conclusion

Genetic selection for enhanced growth in chickens has affected embryonic activity and the expression patterns of IGF-I and myogenic factors in a muscle-specific manner.

Supporting Evidence

  • Broilers showed raised embryonic activity from ED8 and were heavier by hatch.
  • MyoD and IGF-I mRNA levels were altered in a muscle-dependent manner.
  • Cellular characteristics were altered accordingly.

Takeaway

This study looked at how different types of chickens grow and develop their muscles. It found that broiler chickens grow faster and have different muscle characteristics compared to egg-laying chickens.

Methodology

The study used 112 fertilized chicken eggs, comparing broiler and layer strains, measuring muscle mass and cellular characteristics at various embryonic days.

Limitations

The study did not extend beyond embryonic day 11 for motility measurements due to physical constraints of the egg shell.

Participant Demographics

Chick embryos from two strains: broilers (Ross) and layers (White Leghorn).

Statistical Information

P-Value

p<0.0001

Statistical Significance

p<0.0001

Digital Object Identifier (DOI)

10.1016/j.diff.2011.05.012

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