Maternal Obesity and Developmental Programming of Metabolic Disorders in Offspring: Evidence from Animal Models
2011
Maternal Obesity and Its Effects on Offspring's Health
publication
10 minutes
Evidence: moderate
Author Information
Author(s): Li M., Sloboda D. M., Vickers M. H.
Primary Institution: Liggins Institute and the National Research Centre for Growth and Development, University of Auckland
Hypothesis
Does maternal obesity during pregnancy increase the risk of metabolic disorders in offspring?
Conclusion
Maternal obesity is linked to a higher risk of obesity and metabolic disorders in offspring.
Supporting Evidence
- Maternal obesity is associated with increased risk of obesity in offspring.
- Animal models show that maternal high-fat diets lead to metabolic disorders in offspring.
- Interventions during pregnancy may help reduce the risk of obesity in children.
Takeaway
If a mom is overweight while pregnant, her baby might have a higher chance of being overweight and having health problems later.
Methodology
The study reviews various animal models to understand how maternal obesity affects offspring health.
Limitations
The study primarily focuses on animal models, which may not fully represent human outcomes.
Digital Object Identifier (DOI)
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