Mycobacterium tuberculosis Infection as a Zoonotic Disease: Transmission between Humans and Elephants
1998

Transmission of Tuberculosis from Elephants to Humans

Sample size: 22 publication Evidence: moderate

Author Information

Author(s): Kathleen Michalak, Connie Austin, Sandy Diesel, J. Maichle Bacon, Phil Zimmerman, Joel N. Maslow

Primary Institution: McHenry County Department of Health

Hypothesis

Can Mycobacterium tuberculosis be transmitted from elephants to humans?

Conclusion

The study indicates that M. tuberculosis can be transmitted between humans and elephants, as evidenced by DNA fingerprinting.

Supporting Evidence

  • Eleven out of 22 handlers tested positive for tuberculosis.
  • DNA fingerprinting showed identical patterns between elephant and human isolates.
  • Handlers had close contact with infected elephants, increasing transmission risk.

Takeaway

This study shows that elephants can get tuberculosis and can pass it to people who take care of them.

Methodology

An epidemiologic investigation was conducted, including TB screening of handlers and molecular analysis of isolates.

Limitations

The original source of infection for both elephants and humans is unknown.

Participant Demographics

22 animal handlers, including 12 elephant handlers and 10 tiger handlers.

Want to read the original?

Access the complete publication on the publisher's website

View Original Publication