Identification of PI-2 Pili in Mitis Group Streptococci
Author Information
Author(s): Zähner Dorothea, Gandhi Ashish R., Yi Hong, Stephens David S.
Primary Institution: Division of Infectious Diseases, Department of Medicine, Atlanta, Georgia, United States of America
Hypothesis
The study investigates the presence and characteristics of PI-2 pili in Mitis group streptococci.
Conclusion
This research identifies PI-2 pili in Mitis group streptococci, highlighting their role in horizontal gene transfer and potential pathogenic traits.
Supporting Evidence
- PI-2 pili were identified in strains of S. oralis and S. mitis.
- The study revealed significant genetic variability in the pilus proteins among different strains.
- PI-2 pili may play a role in the adhesion and colonization of host tissues.
Takeaway
Scientists found special hair-like structures called pili on certain bacteria in the mouth, which help them stick to surfaces and may play a role in causing diseases.
Methodology
The study involved genomic sequencing, PCR identification, and Western blot analysis to detect PI-2 pili in various strains of Mitis group streptococci.
Limitations
The study does not address the functional implications of the identified pili in disease processes.
Digital Object Identifier (DOI)
Want to read the original?
Access the complete publication on the publisher's website