Asymptomatic Bacteriuria in Children with Sickle Cell Anemia
Author Information
Author(s): Chukwu Bartholomew F, Okafor Henrietta U, Ikefuna Anthony N
Primary Institution: University of Nigeria Teaching Hospital, Enugu
Hypothesis
What is the prevalence of asymptomatic bacteriuria in children with sickle cell anemia compared to those with normal hemoglobin?
Conclusion
Children with sickle cell anemia are three times more likely to have asymptomatic bacteriuria than those with normal hemoglobin.
Supporting Evidence
- 6% of children with sickle cell anemia had significant bacteriuria.
- 83.3% of those with bacteriuria were females.
- Escherichia coli was the most common organism isolated.
Takeaway
Kids with sickle cell anemia can get urinary infections without showing symptoms, and it's more common in girls. We need to check them regularly.
Methodology
The study screened 100 children with sickle cell anemia and 100 with normal hemoglobin for asymptomatic bacteriuria using midstream urine samples.
Potential Biases
Potential bias due to selection of participants from a single hospital and exclusion of those with recent antibiotic use.
Limitations
The study may not represent all children with sickle cell anemia due to the specific location and sample size.
Participant Demographics
100 children with sickle cell anemia (57 males, 43 females) and 100 children with normal hemoglobin aged 2-12 years.
Statistical Information
P-Value
0.04
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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