Bacterial Resistance to Ciprofloxacin in Greece: Results from the National Electronic Surveillance System
1999

Ciprofloxacin Resistance in Greece

Sample size: 11097 publication Evidence: moderate

Author Information

Author(s): A.C. Vatopoulos, V. Kalapothaki, N.J. Legakis

Primary Institution: Athens University

Hypothesis

What are the national trends and local differences in the epidemiology of quinolone resistance in Greece?

Conclusion

Greece has high rates of ciprofloxacin resistance among various bacterial species, particularly in intensive care units.

Supporting Evidence

  • High rates of ciprofloxacin resistance were found in intensive care units compared to other wards.
  • Most ciprofloxacin-resistant strains were also multidrug resistant.
  • Resistance rates varied significantly by hospital and patient setting.

Takeaway

Doctors found that many bacteria in Greece are becoming resistant to a common antibiotic called ciprofloxacin, especially in hospitals.

Methodology

The study analyzed ciprofloxacin susceptibility data from 17 hospitals using routine antibiotic sensitivity tests.

Potential Biases

Different antibiotics tested in each hospital and varying susceptibility testing methods may introduce bias.

Limitations

The study is based on routine data from microbiology labs, which may vary between hospitals and limit comparisons.

Participant Demographics

Data included isolates from medical wards, surgical wards, intensive care units, and outpatient departments.

Statistical Information

P-Value

0.00097

Statistical Significance

p<0.01

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