Diabetic fetopathy associated with bilateral adrenal hyperplasia and ambiguous genitalia: a case report
2008

Diabetic Fetopathy with Ambiguous Genitalia: A Case Report

Sample size: 1 publication Evidence: low

Author Information

Author(s): Tantbirojn Patou, Taweevisit Mana, Sritippayawan Suchila, Uerpairojkit Boonchai

Primary Institution: Chulalongkorn University

Hypothesis

Can bilateral adrenal hyperplasia be a novel feature of diabetic fetopathy?

Conclusion

This case report describes a rare instance of diabetic fetopathy associated with ambiguous genitalia and bilateral adrenal hyperplasia.

Supporting Evidence

  • Maternal diabetes can lead to various fetal malformations.
  • This is the first report of ambiguous genitalia associated with diabetic fetopathy.
  • The newborn had multiple anomalies including holoprosencephaly and polydactyly.
  • Congenital adrenal hyperplasia is a common cause of ambiguous genitalia.

Takeaway

A baby was born with unusual body features because the mother had diabetes during pregnancy, which can cause problems for the baby.

Methodology

Case report detailing the clinical presentation, ultrasound findings, and autopsy results.

Limitations

The investigation of specific precursor metabolites for adrenal hyperplasia was not performed.

Participant Demographics

19-year-old Thai primigravida with a family history of diabetes.

Digital Object Identifier (DOI)

10.1186/1752-1947-2-251

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