Tight Glucose Control Reduces Kidney Problems in Heart Surgery Patients
Author Information
Author(s): Patrick Lecomte, Bruno Van Vlem, Jose Coddens, Guy Cammu, Guy Nollet, Frank Nobels, Hugo Vanermen, Luc Foubert
Primary Institution: Onze-Lieve-Vrouw Hospital, Aalst, Belgium
Hypothesis
Does tight perioperative glucose control reduce renal impairment and failure in non-diabetic cardiac surgical patients?
Conclusion
Tight perioperative blood glucose control significantly reduces the incidence of renal impairment and failure in non-diabetic cardiac surgical patients.
Supporting Evidence
- Tight glycemic control reduced the incidence of renal impairment from 24.4% to 11.4%.
- The need for postoperative dialysis decreased from 3.9% in the Control group to 0.7% in the Insulin group.
- 30-day mortality was lower in the Insulin group (1.2%) compared to the Control group (3.6%).
- Mean blood glucose levels were significantly lower in the Insulin group throughout the study.
Takeaway
Keeping blood sugar levels steady during and after heart surgery helps prevent kidney problems for patients who don't have diabetes.
Methodology
Retrospective analysis of two groups of cardiac surgery patients, one with tight glycemic control and one without.
Potential Biases
Potential biases due to the non-randomized design and differences in patient management.
Limitations
The study is retrospective and not randomized, which may affect the validity of the results.
Participant Demographics
Patients undergoing cardiac surgery, including both diabetic and non-diabetic individuals.
Statistical Information
P-Value
p < 0.01
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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