Living with muscular dystrophy: health related quality of life consequences for children and adults
2007

Health Related Quality of Life in Muscular Dystrophy Patients

Sample size: 107 publication 10 minutes Evidence: moderate

Author Information

Author(s): Grootenhuis Martha A, Boone Judith, van der Kooi Anneke J

Primary Institution: Emma Children's Hospital AMC, Amsterdam

Hypothesis

HRQoL will be affected on all domains in children and adults with muscular dystrophy.

Conclusion

Having muscular dystrophy negatively influences health-related quality of life across several domains.

Supporting Evidence

  • Children with muscular dystrophy reported worse HRQoL on motor functioning and autonomy compared to healthy peers.
  • Adults with muscular dystrophy had lower HRQoL scores compared to the general population.
  • Significant differences in HRQoL were found between different types of muscular dystrophy.

Takeaway

Kids and adults with muscular dystrophy have a harder time feeling good about their lives compared to healthy kids and adults.

Methodology

Age-related HRQoL questionnaires were administered to 40 children and 67 adult patients with muscular dystrophies.

Potential Biases

Patients were already participating in another study, which may have positively influenced the response rate.

Limitations

The study has a relatively small sample size and potential selection bias.

Participant Demographics

40 children (ages 8-17) and 67 adults (ages 18-67), predominantly male.

Statistical Information

P-Value

p<0.05

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1186/1477-7525-5-31

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