Epidemic Zoster and AIDS
1996

Epidemic Zoster and AIDS

Sample size: 120 publication Evidence: moderate

Author Information

Author(s): D. M. Morens, A.K. Agarwal, S. Sarkar, S. Panda, R. Detels

Primary Institution: University of Hawaii School of Medicine

Hypothesis

Is zoster a significant indicator of HIV transmission in developing countries?

Conclusion

Zoster outbreaks may serve as a sentinel indicator of community HIV transmission, particularly in areas with limited HIV diagnosis.

Supporting Evidence

  • The Manipur outbreak was associated with a doubling of zoster frequency above background levels.
  • All 20 injecting drug users who developed zoster were found to be HIV positive.
  • Increased zoster occurrence associated with HIV transmission has also been seen in Ho Chi Minh City, Vietnam.

Takeaway

When people get a skin rash called zoster, it might mean that there are more cases of HIV in the community, especially among drug users.

Methodology

The study observed zoster occurrences in a group of injecting drug users and correlated it with HIV prevalence.

Limitations

The study is based on observations from specific outbreaks and may not be generalizable.

Participant Demographics

Males aged 12-44 years old with high HIV prevalence.

Want to read the original?

Access the complete publication on the publisher's website

View Original Publication