Bacterial Meningitis Incidence in Lazio, Italy (2001–2005)
Author Information
Author(s): Giorgi Rossi Paolo, Mantovani Jessica, Ferroni Eliana, Forcina Antonio, Stanghellini Elena, Curtale Filippo, Borgia Piero
Primary Institution: Agency for Public Health, Lazio Region, Rome, Italy
Hypothesis
The study aimed to estimate the incidence of bacterial meningitis by aetiological agent in Lazio, Italy, from 2001 to 2005.
Conclusion
The integrated surveillance system showed a decrease in H. influenzae b meningitis incidence due to mass vaccination of newborns.
Supporting Evidence
- 944 cases of meningitis were reported during the study period.
- The overall incidence was 3.7/100,000.
- Children under 1 year had the highest incidence at 50.3/100,000.
- The study estimated underreporting at 17.2% of the overall incidence.
Takeaway
This study looked at how many people got bacterial meningitis in Lazio, Italy, and found that vaccines helped reduce some types of it.
Methodology
Data were collected from hospital surveillance, laboratory information systems, mandatory disease notifications, and hospital information systems.
Potential Biases
Underreporting was noted, especially among foreign cases and probable hospital infections.
Limitations
The study did not include death certificates among the sources, which may affect mortality data accuracy.
Participant Demographics
The population of Lazio is approximately 5.3 million, with a focus on children under 5 years old.
Statistical Information
P-Value
p<0.05
Confidence Interval
95% CI 104–125
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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