Reirradiation of head and neck cancer focusing on hypofractionated stereotactic body radiation therapy
2011

Reirradiation of Head and Neck Cancer with Stereotactic Body Radiation Therapy

publication Evidence: moderate

Author Information

Author(s): Yamazaki Hideya, Kodani Naohiro, Ogita Mikio, Sato Kengo, Himei Kengo

Primary Institution: Department of Radiology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine

Hypothesis

Reirradiation is a feasible option for patients with head and neck cancer who have limited treatment options.

Conclusion

Reirradiation using modern techniques like hypofractionated stereotactic body radiation therapy can be effective but carries risks of severe complications.

Supporting Evidence

  • Reirradiation can be delivered using various techniques including external beam radiotherapy and brachytherapy.
  • Severe late adverse reactions are more common with reirradiation than with initial radiation therapy.
  • Studies report a 20-40% risk of severe late complications associated with reirradiation.

Takeaway

This study looks at how doctors can safely give radiation treatment again to patients with head and neck cancer, even if they have already had radiation before.

Methodology

The study reviewed literature on reirradiation techniques and outcomes for head and neck cancer patients.

Limitations

The study highlights the potential for severe late complications and the need for careful patient selection.

Digital Object Identifier (DOI)

10.1186/1748-717X-6-98

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