Squamous carcinoma of the head and neck: cured fraction and median survival time as functions of age, sex, histologic type, and node status
1993

Survival and Cure Rates in Head and Neck Cancer

Sample size: 2073 publication Evidence: moderate

Author Information

Author(s): J. W. Gamell, A.S. Jones

Primary Institution: Veterans Administration Medical Center and University of Louisville, School of Medicine

Hypothesis

The study investigates how age, sex, histologic type, and node status affect the cured fraction and median survival time in patients with squamous carcinoma of the head and neck.

Conclusion

The cured fraction is mainly influenced by histologic type and node status, while median survival time is primarily affected by age and node status.

Supporting Evidence

  • Cured fraction is primarily a function of histologic type and node status.
  • Median survival time is primarily a function of age and node status.
  • Patient sex was related to likelihood of cure, but this association was of marginal significance.

Takeaway

This study looks at how different factors like age and tumor type can affect how long patients with head and neck cancer live and how many can be cured.

Methodology

The study used a multivariate lognormal survival model to analyze data from 2,073 patients with squamous cell carcinoma of the head and neck.

Limitations

The study's findings may be limited by the complexities of multivariate survival analysis and the need for further investigation.

Participant Demographics

{"male_percentage":70,"female_percentage":30,"average_age_male":61.8,"average_age_female":62.1}

Statistical Information

Statistical Significance

p<0.05

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