Postulated Role of Vasoactive Neuropeptide-Related Immunopathology of the Blood Brain Barrier and Virchow-Robin Spaces in the Aetiology of Neurological-Related Conditions
2008
Role of Vasoactive Neuropeptides in Neurological Conditions
publication
Author Information
Author(s): D. R. Staines, E. W. Brenu, S. Marshall-Gradisnik
Primary Institution: Gold Coast Population Health Unit, Queensland Health
Hypothesis
Autoimmunity of vasoactive neuropeptides or their receptors may contribute to the aetiology of neurological-related conditions.
Conclusion
Vasoactive neuropeptides play a critical role in maintaining the integrity of the blood-brain barrier and may be linked to various neurological disorders.
Supporting Evidence
- Vasoactive neuropeptides are important for blood vessel function in the central nervous system.
- Disruption of the blood-brain barrier is known in certain pathological states.
- Vasoactive neuropeptides may assist in immune regulation of the brain and spinal cord.
Takeaway
Vasoactive neuropeptides help keep our brain's protective barriers strong, and if they don't work right, it could lead to brain problems.
Digital Object Identifier (DOI)
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