The Role of Th17 in Neuroimmune Disorders: Target for CAM Therapy. Part I
2011

The Role of Th17 in Neuroimmune Disorders: Target for CAM Therapy

publication Evidence: moderate

Author Information

Author(s): Aristo Vojdani, Jama Lambert

Primary Institution: Immunosciences Lab., Inc.

Hypothesis

Understanding the role of Th17 cells in autoimmune diseases can help design CAM therapies targeting these cells.

Conclusion

Th17 cells and their cytokines play a significant role in the pathogenesis of neuroimmune disorders, suggesting that targeting them may be beneficial in treatment.

Supporting Evidence

  • Th17 cells produce IL-17, which contributes to the pathogenesis of multiple autoimmune diseases.
  • Targeting Th17 cells may help repair the intestinal and blood-brain barriers in patients with autoimmunities.
  • IL-17 is linked to various inflammatory and autoimmune diseases, including multiple sclerosis.

Takeaway

Th17 cells are a type of immune cell that can cause inflammation and are important in diseases like multiple sclerosis. Finding ways to target these cells could help treat these diseases.

Methodology

The article reviews the role of Th17 cells in autoimmune diseases and discusses potential CAM therapies targeting these cells.

Limitations

The study primarily focuses on the role of Th17 cells without extensive empirical data or clinical trials.

Digital Object Identifier (DOI)

10.1093/ecam/nep062

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