Clusters of spatial, temporal, and space-time distribution of hemorrhagic fever with renal syndrome in Liaoning Province, Northeastern China
2011

Study of Hemorrhagic Fever Clusters in Liaoning Province, China

Sample size: 20227 publication 10 minutes Evidence: high

Author Information

Author(s): Wu Wei, Guo Junqiao, Guan Peng, Sun Yingwei, Zhou Baosen

Primary Institution: Department of Epidemiology, School of Public Health, China Medical University

Hypothesis

What are the spatial, temporal, and space-time distribution patterns of hemorrhagic fever with renal syndrome (HFRS) in Liaoning Province, China?

Conclusion

The study found significant spatial, temporal, and space-time clusters of HFRS in Liaoning Province, which can help improve public health strategies.

Supporting Evidence

  • The study identified one most likely cluster and four secondary clusters of HFRS cases.
  • Moran's I statistic was significant at 0.001, indicating non-random distribution of HFRS.
  • The average annual incidence of HFRS was 3.6 cases per 100,000 persons over the study period.
  • The most likely temporal cluster was identified between 1998-2001.

Takeaway

This study looked at where and when people got sick from a disease called HFRS in a specific area of China, helping to find patterns that can keep people safer.

Methodology

Spatial autocorrelation analysis and spatial, temporal, and space-time cluster analysis were conducted using data from 1988 to 2001.

Potential Biases

Potential biases due to the ecological nature of the study and reliance on reported case data.

Limitations

The study is ecological, which may introduce ecological fallacy and variability in data quality over time and place.

Participant Demographics

Data included HFRS cases from various counties and districts in Liaoning Province, China.

Statistical Information

P-Value

0.001

Statistical Significance

p<0.001

Digital Object Identifier (DOI)

10.1186/1471-2334-11-229

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