Erythema nodosum as first clinical sign of acute Borrelia burgdorferi infection
2024

Erythema Nodosum as a Sign of Lyme Disease

Sample size: 1 publication Evidence: low

Author Information

Author(s): Kordeva Simona, Ivanov Lyudmil, Broshtilova Valentina, Tchernev Georgi

Primary Institution: Onkoderma- Clinic for Dermatology, Venereology and Dermatologic Surgery, Bulgaria

Hypothesis

Can erythema nodosum be an initial sign of acute Borrelia burgdorferi infection?

Conclusion

Erythema nodosum, although rare, can serve as a valuable diagnostic marker for Borrelia infection.

Supporting Evidence

  • Erythema nodosum is a rare initial sign of Borrelia infection.
  • Serological testing confirmed Borrelia infection in the patient.
  • Histological findings were consistent with erythema nodosum.

Takeaway

A 78-year-old woman had painful lumps on her legs after a tick bite, which turned out to be a sign of Lyme disease. Treating her helped the lumps go away.

Methodology

The case report involved clinical evaluation, serological testing, and histological examination.

Limitations

The rarity of erythema nodosum as a sign of Lyme disease may limit generalizability.

Participant Demographics

78-year-old female patient.

Digital Object Identifier (DOI)

10.1016/j.bjid.2024.103877

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