Fluid Treatments with Different Sodium Concentration in Children with Diabetic Ketoacidosis
Author Information
Author(s): Savaş-Erdeve Şenay, Berberoğlu Merih, Oygar Pembe, Şıklar Zeynep, Kendirli Tanıl
Primary Institution: Ankara University School of Medicine, Department of Pediatrics
Hypothesis
Does the administration of rehydration fluids with different sodium concentrations affect the treatment outcomes in children with diabetic ketoacidosis?
Conclusion
Rehydration fluids with sodium concentrations of 75 or 100 mEq/L did not show any differences in efficacy or safety for children with diabetic ketoacidosis.
Supporting Evidence
- Changes in blood glucose levels did not differ significantly between the two groups.
- None of the patients developed cerebral edema during the study.
- The duration of a low pH level was shorter in the group receiving 100 mEq/L sodium, but not statistically significant.
Takeaway
This study looked at two types of fluids given to kids with a serious diabetes problem, and found that it didn't matter which one was used; both worked the same.
Methodology
The study assessed 32 children with DKA, comparing the effects of two different sodium concentrations in rehydration fluids.
Limitations
The study had a small sample size and was retrospective in design.
Participant Demographics
Children under 18 years of age with diabetic ketoacidosis.
Statistical Information
P-Value
0.74
Statistical Significance
p=0.74
Digital Object Identifier (DOI)
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