Reproducibility of Patient Setup in Prostate Cancer Radiotherapy
Author Information
Author(s): Krengli Marco, Gaiano Simone, Mones Eleonora, Ballarè Andrea, Beldì Debora, Bolchini Cesare, Loi Gianfranco
Primary Institution: University Hospital Maggiore della Carità, Novara, Italy
Hypothesis
Can a surface image registration system improve the reproducibility of patient setup in conformal radiotherapy for prostate cancer?
Conclusion
The surface image registration system is a simple, fast, non-invasive, and reproducible method for analyzing setup alignment in prostate cancer radiotherapy.
Supporting Evidence
- The mean random and systematic errors were low, indicating high reproducibility.
- Correlation factors between errors measured by AlignRT and EPID ranged from 0.77 to 0.92.
- The positioning error exceeded 5 mm in 14.1% of measurements along the X axis.
Takeaway
This study shows that using a special camera system can help doctors set up prostate cancer patients for treatment more accurately and consistently.
Methodology
The study analyzed the setup reproducibility of 16 prostate cancer patients using a surface image registration system, comparing EPID images with reference 3D surface images.
Limitations
The study did not analyze rotational errors or other factors affecting patient setup, and the sample size was small.
Participant Demographics
Patients aged 61 to 78 years, median age 73, with Gleason scores from 6 to 9 and PSA levels from 2 to 75 ng/ml.
Digital Object Identifier (DOI)
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