A child presenting with acute renal failure secondary to a high dose of indomethacin: a case report
2009
Acute Renal Failure in a Child Due to High Dose of Indomethacin
Sample size: 1
publication
Evidence: low
Author Information
Author(s): González Felipe, López-Herce Jesús, Moraleda Cinta
Primary Institution: Hospital General Universitario Gregorio Marañón, Universidad Complutense de Madrid, Madrid, Spain
Hypothesis
Can high doses of indomethacin cause acute renal failure in children?
Conclusion
High doses of indomethacin can lead to acute renal failure, but with proper treatment, recovery is possible.
Supporting Evidence
- The infant received a dose of indomethacin that was 50 to 100 times higher than the therapeutic dose.
- Continuous venovenous renal replacement therapy was required due to acute renal failure.
- The child achieved complete recovery of renal function with no sequelae.
Takeaway
A baby took too much indomethacin medicine and got really sick, but doctors helped him get better.
Methodology
Case report detailing the clinical presentation, treatment, and recovery of a child after a medication error.
Potential Biases
Potential bias due to the single case report format.
Limitations
Only one case is reported, limiting generalizability.
Participant Demographics
20-day-old male infant.
Digital Object Identifier (DOI)
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