Osteochondritis dissecans and Osgood Schlatter disease in a family with Stickler syndrome
2009

Osteochondritis Dissecans and Osgood Schlatter Disease in a Family with Stickler Syndrome

Sample size: 2 publication Evidence: low

Author Information

Author(s): Al Kaissi Ali, Klaushofer Klaus, Grill Franz

Primary Institution: Ludwig-Boltzmann Institute of Osteology at the Hanusch Hospital of WGKK and AUVA Trauma Centre Meidling, Vienna, Austria

Hypothesis

The study aims to explore the relationship between osteochondritis dissecans (OCD) and Osgood Schlatter syndrome (OSS) in patients with Stickler syndrome.

Conclusion

The study found that OCD and OSS are significant musculoskeletal consequences of Stickler syndrome, suggesting a localized manifestation of a more generalized epiphyseal dysplasia.

Supporting Evidence

  • The study describes two family members with Stickler syndrome presenting with OCD and OSS.
  • MRI imaging was emphasized for predicting articular lesion healing potential.
  • The findings suggest that the full clinical criteria of Stickler syndrome may not always be present.

Takeaway

This study looked at two family members with Stickler syndrome who had knee problems, showing that their issues were linked to a bigger problem with their bones.

Methodology

Clinical and radiographic examinations were conducted, with a focus on MRI imaging.

Limitations

The study is limited by the small sample size and lack of genetic analysis.

Participant Demographics

Two family members, a 15-year-old male and a 49-year-old female, both with Stickler syndrome.

Digital Object Identifier (DOI)

10.1186/1546-0096-7-4

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