Muscle Atrophy and Quality of Life in Patients with Restless Legs Syndrome
Author Information
Author(s): Giannaki Christoforos D., Sakkas Giorgos K., Karatzaferi Christina, Hadjigeorgiou Georgios M., Lavdas Eleftherios, Liakopoulos Vassilios, Tsianas Nikolaos, Koukoulis Georgios N., Koutedakis Yiannis, Stefanidis Ioannis
Primary Institution: University of Thessaly
Hypothesis
Restless Legs Syndrome negatively affects muscle quantity and quality in hemodialysis patients.
Conclusion
Patients with Restless Legs Syndrome showed increased muscle atrophy and impaired quality of life primarily due to mental health and sleep-related issues.
Supporting Evidence
- 30 out of 70 patients were diagnosed with Restless Legs Syndrome.
- RLS patients reported significantly lower quality of life scores.
- Muscle size was significantly reduced in the RLS group compared to non-RLS.
- Depression scores were higher in RLS patients.
- Sleep quality was significantly impaired in RLS patients.
Takeaway
Patients on dialysis with Restless Legs Syndrome have weaker muscles and feel worse because they can't sleep well and feel sad.
Methodology
The study assessed 70 hemodialysis patients, dividing them into RLS and non-RLS groups, evaluating muscle size, quality of life, and depression through various tests and questionnaires.
Limitations
The PLMS index was assessed from a single overnight study, which may not accurately reflect variability across nights.
Participant Demographics
70 hemodialysis patients (51 male, 19 female, average age 54.1 years).
Statistical Information
P-Value
p<0.05
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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