How Low Power Laser Irradiation Helps Cells Grow
Author Information
Author(s): Gao Xuejuan, Xing Da
Primary Institution: MOE Key Laboratory of Laser Life Science & Institute of Laser Life Science, South China Normal University, Guangzhou, PR China
Hypothesis
Low power laser irradiation (LPLI) promotes cell proliferation through specific molecular mechanisms.
Conclusion
Low power laser irradiation enhances cell proliferation by activating mitochondrial signaling pathways and various growth factors.
Supporting Evidence
- LPLI promotes proliferation in various cell types, including fibroblasts and endothelial cells.
- Activation of mitochondrial respiratory chain components is crucial for LPLI-induced proliferation.
- Signaling pathways like TPKR/Ras/Raf/MEK/ERK are involved in the proliferation process.
- LPLI increases the expression of growth factors and cytokines related to cell proliferation.
- Different wavelengths of light can have varying effects on cell proliferation.
Takeaway
Using low power lasers can help cells grow faster by making them more active and helping them communicate better.
Methodology
The review discusses various studies on the molecular mechanisms of LPLI-induced proliferation, focusing on mitochondrial photoacceptors and signaling pathways.
Limitations
The review primarily summarizes existing studies and may not include all recent findings or advanced techniques.
Digital Object Identifier (DOI)
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