Framework of Collagen Type I – Vasoactive Vessels Structuring Invariant Geometric Attractor in Cancer Tissues: Insight into Biological Magnetic Field Geometric Invariant Attractor
2009

Understanding Collagen and Blood Vessels in Cancer Tissues

Sample size: 549 publication Evidence: high

Author Information

Author(s): Díaz Jairo A., Murillo Mauricio F., Jaramillo Natalia A.

Primary Institution: University Cooperative of Colombia

Hypothesis

How do the geometric structures of collagen and blood vessels interact in cancer tissues?

Conclusion

The study reveals that collagen type I and vascular structures in cancer tissues form complex geometric patterns that may influence tumor behavior.

Supporting Evidence

  • Over 95% of the analyzed tumors showed a correlation between vascular patterns and geometric structures.
  • The study identified specific patterns of vascular behavior associated with tumor activity.
  • Immunostaining revealed significant differences in vascular reactivity in tumor tissues.

Takeaway

This study shows that in cancer, the way blood vessels and collagen are arranged can affect how the tumor grows and behaves.

Methodology

The study involved analyzing 549 malignant tumors for geometric patterns of collagen and vascular structures using histopathology and immunohistochemistry.

Statistical Information

P-Value

0.000001

Confidence Interval

92.83%-96.67%

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1371/journal.pone.0004506

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