Comparing Dacron® and PTFE in Vascular Surgery
Author Information
Author(s): Stephanie Roll, Jacqueline Müller-Nordhorn, Thomas Keil, Hans Scholz, Daniela Eidt, Wolfgang Greiner, Stefan N. Willich
Primary Institution: Charité University Medical Center, Berlin, Germany
Hypothesis
Which synthetic material, Dacron® or PTFE, is more effective for bypass grafting in peripheral vascular surgery?
Conclusion
There is no evidence of an advantage of one synthetic material over the other for bypass grafting.
Supporting Evidence
- Nine randomized controlled trials were included in the analysis.
- Two trials showed significant differences in primary patency, one favoring Dacron® and one favoring PTFE.
- Seven trials did not show significant differences between the two materials.
- Meta-analysis yielded a hazard ratio of 1.04 for primary patency with no significant heterogeneity.
Takeaway
Doctors wanted to find out if Dacron® or PTFE is better for surgery to help blood flow in legs, but they found that both work about the same.
Methodology
A systematic review and meta-analysis of randomized controlled trials comparing Dacron® and PTFE grafts.
Potential Biases
Funding sources were not specified in some trials, which may introduce bias.
Limitations
The included trials had small sample sizes and varied methods for determining patency rates.
Participant Demographics
The studies included patients with symptomatic peripheral arterial disease.
Statistical Information
P-Value
0.32
Confidence Interval
[0.85;1.28]
Statistical Significance
p = 0.32
Digital Object Identifier (DOI)
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