Protein Intake and Mortality in Older Adults with Chronic Kidney Disease
Author Information
Author(s): Carballo-Casla Adrián, Avesani Carla Maria, Beridze Giorgi, Ortolá Rosario, Carrero Juan-Jesús, Rodríguez-Artalejo Fernando, Vetrano Davide Liborio, Calderón-Larrañaga Amaia
Primary Institution: Karolinska Institutet
Hypothesis
Higher protein intake may reduce mortality in older adults with chronic kidney disease.
Conclusion
Higher protein intake, especially from plant sources, is linked to lower mortality in older adults with chronic kidney disease.
Supporting Evidence
- Higher total protein intake was associated with lower mortality among participants with CKD.
- Plant protein showed a stronger inverse association with mortality than animal protein.
- No significant interactions between protein intake and CKD were found among participants without CKD.
Takeaway
Eating more protein, especially from plants, can help older people with kidney problems live longer.
Methodology
Data from three cohorts were analyzed using Cox proportional hazards regression models.
Potential Biases
Potential biases in dietary reporting and cohort selection.
Limitations
The study may not account for all confounding factors affecting mortality.
Participant Demographics
Community-dwelling adults aged 60 and older, with and without chronic kidney disease.
Statistical Information
Confidence Interval
0.75 (0.62,0.92)
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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