Reliability of home CPAP titration with different automatic CPAP devices
2008

Comparing Automatic CPAP Machines for Sleep Apnea Treatment

Sample size: 16 publication Evidence: moderate

Author Information

Author(s): Frédéric Sériès, Julie Plante, Yves Lacasse

Primary Institution: Institut Universitaire de cardiologie et de pneumologie de l'Université Laval

Hypothesis

How do different automatic CPAP machines compare in their pressure behavior and recommendations during home titration?

Conclusion

Pressure behavior and recommendations significantly differ between automatic CPAP machines after both one night and one week of home titration.

Supporting Evidence

  • The median pressure value was significantly lower with machine GK 420 than with the other devices.
  • The maximal pressure obtained over the one-week titration was significantly higher with Remstar Auto than with the two other machines.
  • The variance in pressure recommendation significantly differed between the three machines after one night.

Takeaway

Different machines that help people breathe at night can give different pressure settings, which might affect how well they work.

Methodology

Sixteen untreated obstructive sleep apnea patients were randomly allocated to one of three automatic CPAP machines for a one-week home titration trial in a crossover design.

Potential Biases

Potential bias due to the absence of in-lab assessment of positive pressure needs.

Limitations

Patient selection criteria and lack of in-lab evaluation of positive pressure requirements.

Participant Demographics

14 males and 2 females, average age 49 years, average BMI 30.8.

Statistical Information

P-Value

p<0.05

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1186/1465-9921-9-56

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